Drug Pipeline

Apixaban selectively inhibits factor Xa in its free and bound forms, independant of antithrombin III. Apixaban also inhibits prothrominase. These effects prevent the formation of a thrombus.

Coagulation factor VII exogenous protein; Vitamin K-dependent protein S exogenous protein; Vitamin K-dependent protein C exogenous protein; Coagulation factor IX exogenous protein; Thrombin exogenous protein

Tissue factor pathway inhibitor inhibitor

Tissue factor pathway inhibitor inhibitor

L-Alturonic Acid is a carbohydrate acid derivative.

HEMLIBRA bridges activated factor IX and factor X to restore the function of missing activated factor VIII that is needed for effective hemostasis.

Cyclooxygenase-2 inhibitor

Coagulation factor IX exogenous protein

Upon binding of desmopressin to V2 receptors in the basolateral membrane of the cells of the distal tubule and collecting ducts of the nephron, adenylyl cyclase is stimulated. The resulting intracellular cascades in the collecting duct lead to increased rate of insertion of water channels, called aquaporins, into the lumenal membrane and enhanced the permeability of the membrane to water.