Clinical Trials

50 trials registered for Hemophilia B, severe

HOPE-B: Trial of AMT-061 in Severe or Moderately Severe Hemophilia B Patients
NCT03569891Phase 3CSL Behring
Completed
In Vitro Correction of Thrombin Generation by Concizumab (Anti-TFPI) for Severe Hemophilia Patients
NCT05617209N/ACentre Hospitalier Universitaire de Saint Etienne
Completed
KN057 Multiple Dose Study in Moderately Severe to Severe Hemophilia
NCT05421429Phase 2Suzhou Alphamab Co., Ltd.
Completed
Long-Term Safety and Efficacy of rFIXFc in the Prevention and Treatment of Bleeding Episodes in Previously Treated Participants With Hemophilia B
NCT01425723Phase 3Bioverativ Therapeutics Inc.
Completed
Nonacog Alfa Prophylaxis And Treatment Of Bleeding Episodes In Previously Treated Patients With Hemophilia B
NCT04286412Phase 4Pfizer
Completed
PF-06741086 Long-term Treatment in Severe Hemophilia
NCT03363321Phase 2Pfizer
Completed
PF-06741086 Multiple Dose Study in Severe Hemophilia
NCT02974855Phase 2Pfizer
Completed
Pivotal Study (Pharmacokinetics, Efficacy, Safety) of BAX 326 (rFIX) in Hemophilia B Patients
NCT01174446Phase 3Baxalta now part of Shire
Completed
Study Comparing On-Demand Treatment With Two Prophylaxis Regimens Of BeneFIX In Patients With Severe Hemophilia B
NCT00364182Phase 3Pfizer
Completed
Study Evaluating B-Domain Deleted Recombinant Factor VIII (BDDrFVIII, ReFacto AF) in Patients With Hemophilia A Undergoing Elective Major Surgery
NCT00243659Phase 3Wyeth is now a wholly owned subsidiary of Pfizer
Completed
Study Evaluating of Recombinant Human Factor IX (BeneFIX) and a New Formulation of BeneFIX (rFIX-R) in Moderate to Severe Hemophilia B
NCT00093210Phase 3Wyeth is now a wholly owned subsidiary of Pfizer
Completed
Study Evaluating rFIX; BeneFIX in Severe Hemophilia B
NCT00037557Phase 3Wyeth is now a wholly owned subsidiary of Pfizer
Completed
Study of FVIIa Variant BAY86-6150 (B0189) in Subjects With Moderate or Severe Hemophilia Types A or B With or Without Inhibitors
NCT01921855Phase 1Bayer
Completed
Study of Recombinant Factor IX Fc Fusion Protein (rFIXFc) in Participants With Hemophilia B
NCT01027364Phase 3Bioverativ Therapeutics Inc.
Completed
Study to Describe the Allergic Reactions to Factor IX in Patients With Hemophilia B
NCT00195221N/AWyeth is now a wholly owned subsidiary of Pfizer
Completed
Study to Determine the Safety and Efficacy of rFIXFc in Previously Untreated Males With Severe Hemophilia B
NCT02234310Phase 3Bioverativ, a Sanofi company
Completed
Trial of AAV5-hFIX in Severe or Moderately Severe Hemophilia B
NCT02396342Phase 1/2CSL Behring
Completed
A Study to Investigate the Safety and Effectiveness of a Coagulation Factor IX Gene Insertion Therapy (REGV131-LNP1265) in Pediatric, Adolescent and Adult Participants With Hemophilia B
NCT06379789Phase 1/2Regeneron Pharmaceuticals
Recruiting
Efficacy and Safety of CSL222 (Etranacogene Dezaparvovec) Gene Therapy in Adults With Hemophilia B With Pretreatment Adeno-associated Virus Serotype 5 (AAV5) Neutralizing Antibodies (Nabs)
NCT06003387Phase 3CSL Behring
Recruiting
Open-Label Extension Study of Marstacimab in Hemophilia Participants With or Without Inhibitors
NCT05145127Phase 3Pfizer
Recruiting
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