Drug Pipeline
22 drugs associated with Phenylketonuria
| Drug | Phase | Sponsor | |
|---|---|---|---|
Palynziq Pegvaliase is a phenylalanine ammonia lyase (PAL) enzyme that temporarily restores the levels of deficient enzyme and reduces blood phenylalanine concentrations by converting phenylalanine to ammonia and _trans_-cinnamic acid. Formed conversion products are metabolized in the liver and later excreted in the urine. | unknown | Emory University | ↗ |
Pegvaliase Pegvaliase is a phenylalanine ammonia lyase (PAL) enzyme that temporarily restores the levels of deficient enzyme and reduces blood phenylalanine concentrations by converting phenylalanine to ammonia and _trans_-cinnamic acid. Formed conversion products are metabolized in the liver and later excreted in the urine. | unknown | Boston Children's Hospital | ↗ |